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Deficiency of this important vitamin can have various causes, such as insufficient dietary intake, for example, in vegetarian or vegan diets, or disturbances in absorption in the gastrointestinal tract due to, for example, Crohn's disease

Trigger fingers and tenosynovitis in the hand and wrist can require: Partial release of tight tunnels Partial flexor tendon excision (removal) in the finger Tenosynovectomy to prevent tendon ruptures Joint Rebalancing In the early stages of rheumatoid arthritis, joints, especially the small joints of the hands and fingers, can become loose and unbalanced, causing deformities and contractures (when the tissue becomes stiff, constricted, and/or shortened) that interfere with function

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Constructs immediately treated with BAPN (day 0) were untestable and resulted in a ruptured construct