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Knowledge of the PK-PD profile of neuroprotective drugs at the BBB/BCSFB level may be helpful to improve the therapeutic window of opportunity to treat TBI and other CNS diseases

The GHR-S1a form is an active 7-transmembrane domain receptor, whereas GHR-S1b form is a truncated 5-transmembrane domain receptor, with no evident psychological function

Following MPTP treatment, irisin was administered to examine its effects on motor function and neural damage in the mice (Fig

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