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Description

Targeting cancer vulnerabilities with high-dose vitamin C

Our proposed receptor activation mechanism also suggests that the conformation of a GHSR ligand around the E124 3.33 -R283 6.55 salt bridge in the cavity II is an important structural determinant for ligand efficacy, providing a molecular foundation for designing novel ghrelin agonists

DOI: 10901185 60

The cells were then washed with PBS, and GSH and GSSG levels were determined by applying the GSH/GSSG-Glo assay according to manufacturer instructions