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Overall, most of the literature reviewed here suggest high heme (and iron) correlate with anti-inflammatory phenotypes

Experiments involving large animals, such as porcine ovarian-insufficiency models, have integrated Cas13 RNA-targeting enzymes with synthetic microRNAs to rectify hormone signaling deficiencies and reinstate folliculogenesis, providing a direct insight into therapeutic potential in species with reproductive physiology akin to that of humans [591]