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This discrepancy of iron chelation worsening neurodegeneration characterised by local iron overload raises a critical question: why does iron chelation block ferroptosis induced by pro-ferroptotic agents such as RSL3 and erastin (where there is no iron elevation in cell culture), yet fail to protect in the context of human neurodegenerative disease where iron is elevated

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Detection of occult acute kidney injury in glucose-6-phosphate dehydrogenase deficiency anemia

doi: 10.1016/j.transproceed.2014.10.045 32 LiuT.-Z.LeeK.-T.ChernC.-L.ChengJ.-T.SternA.TsaiL.-Y