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doi: 10.1007/BF00191904 139 LocheSCambiasoPMerolaBColaoAFaeddaAImbimboBPet al

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635 A double-blind, randomized, placebo-controlled trial of LX-9211 for pain relief and safety in DPN initially found that LX-9211 improved PDPN

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1,86 Large fiber neuropathy Large fiber neuropathy affects larger myelinated A fibers, resulting in sensory and motor deficits

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Close monitoring is advised to avoid exceeding maximum recommended doses, which could lead to systemic toxicity

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