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These small differences in efficacy of BLX2477 may be explained by the 3-log higher IC 50 of BLX2477 for free versus PE-esterified eicosatetraenoic acid (ETE) (Supplemental Figure 3)

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Cellular Senescence Oxytocin reduces senescence markers and clears senescent cells while decreasing pro-inflammatory factors

153155 We showed that knockout mice that had no Rlip gene had 80% loss of GS-E transport activity and markedly increased levels of LOOH and 4HNE in tissues