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The patient developed a fever upon admission

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Specifically, CAR T cells in the day 28 BM of LTR had significantly higher expression of mTOR, pS6, pAKT (mTOR and pAKT pathways) and the metabolic sensor AMPK, as well as significant increases in the fermentative glycolysis enzyme LDHA, the endogenous fatty acid metabolism enzymes SCD1, LAL, and CD45RA, suggesting an effector immunometabolic phenotype

INSULIN RESISTANCE AND OBESITY Healthy -cells actively respond to insulin resistance by modifying both their mass and function to maintain normal glucose levels