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Therefore, pro-apoptotic proteins can be activated and anti-apoptotic proteins can be suppressed by calcitriol/VDR signaling, which may also reduce tumor-associated inflammation by suppressing the cyclooxygenase-2, prostaglandin, and NF-kB pathways

Pediatr Neurol 6:379381

Within cells, arachidonic acid does not exist as a free fatty acid but rather is esterified to the sn 2 position of membrane phospholipids, predominantly phosphatidylcholine and phosphatidylethanolamine