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Semaglutide: Standard shelf life: 30-45 days refrigerated Maximum: 56 days (some clinical protocols allow) More stable than research peptides Pharmaceutical-grade formulations include additional stabilizers Tirzepatide: Standard shelf life: 30-45 days refrigerated Maximum: 56 days Similar stability to semaglutide Important note: Research chemical versions of semaglutide/tirzepatide may be less stable than pharmaceutical versions

After stopping a CYP2D6 inhibitor, as the effects of the inhibitor decline, the codeine plasma concentration will decrease but the active metabolite morphine plasma concentration will increase, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression [see CLINICAL PHARMACOLOGY]