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Acknowledgments The authors would like to express their sincere gratitude to Hao Wang, Cankun Zhou, Yonglian Chen, Jun Lyu, Minqing Feng, and Xiaobin Huang for their valuable contributions to the early stages of this work and for their collaborative support throughout the research process

This review synthesizes current knowledge on the liver-brain crosstalk in AD, emphasizing the mechanistic role of liver in bridging metabolic dysfunction with neurodegeneration and underscores the diagnostic and therapeutic potential of hepatokines in addressing ADs complex pathology

10.1111/jmwh.12220 14 DubalD

Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons