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AD: Alzheimers disease APP: amyloid precursor protein ARE: antioxidant response element A: amyloid- CAT: catalase CEMss: acute lymphoblastic leukemia COX-2 : cyclooxygenase-2 GSH: glutathione HO-1: heme oxygenase-1 IL-1: interleukin-1 Keap1: Kelch-like ECH-associated protein 1 LPS: lipopolysaccharide MDA: malondialdehyde NF-B : nuclear factor-kappa B NO: nitric oxide Nrf2: nuclear factor erythroid 2-related factor 2 PGE 2 : prostaglandin E 2 PPAR-: peroxisome proliferator-activated receptor ROS: reactive oxygen species SOD: superoxide dismutase TNF-: tumor necrosis factor- TQ: thymoquinone The authors would like to state that during the preparation of this manuscript/study, the authors used ChatGPT (OpenAI, version GPT-5) for the purposes of English language editing and grammar refinement with an aimto enhance clarity and readability