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rxlist.com Austedo Keywords Valbenazine Trade Name: Ingrezza Drug Class: Rx of Tardive dyskinesia (monoamine depletor) Mechanism of Action: a selective competitive inhibitor of VMAT2, similar to tetrabenazine the monoamine vesicular monoamine uptake transporter (VMAT2) transports (loads) cytoplasmic monoamine neurotransmitters (dopamine, norepinephrine, histamine, serotonin) into presynaptic storage vesicles found in sympathetic nerve terminals

Consequently, this mechanism suppresses the elevation of Fe 2+ , thereby inhibiting ferroptosis in GSCs

witnessed a doubled GPx1 expression that protected the neuroblastoma cells against 6-hydroxydopamine-induced neurotoxicity

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