glutathione redox reaction cycle dysregulation in Huntington's disease knock-in striatal cells Switching of fluorescence mediated by

Importantly, flow cytometric analysis of MZB both excluded any gene-dosage effect of Gclc expression and confirmed that loss of MZB was independent of any Cre -associated toxicity (Supplementary Fig

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The recognition sequence is cleaved C-terminally after Asn allowing a traceless release of the attached payload if the cargo is conjugated to the C-terminus, while the N-terminus of the linker is coupled to the carrier (Stern et al., 2009