chac1 glutathione CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers Dysregulated lipids homeostasis disrupts CHAC1-mediated

Dysregulated lipids homeostasis disrupts CHAC1 mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer ScienceDirect Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress

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