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In addition, the higher vibration and mechanical detection thresholds at upper and lower limbs reported by different authors indicates the coexistence with distal damage at large myelinated sensory fibers [38, 41, 42]

Das erfindungsgeme Stoffgemisch verhindert weitgehend Vernetzungen (cross-links) von Biomoleklen (Bindegewebe, Proteine, DNA u.a.) beim Diabetes mellitus und besonders auch beim Diabetischen Sptsyndrom (Verhinderung von Amadorikrpern)

Significant physicochemical instability means, that the color, odor, viscosity, pH, or the appearance changed (increased, decreased) more than 10% from the time when the composition was prepared and filled into the final packaging

Therefore, diagnosis relies on a combination of suggestive histological findings