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Safety of intracerebroventricular copper histidine in adult rats

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It has been suggested that the stronger the skin sensitizer the larger the tendency is to modify several nucleophilic sites within the same protein, as this leads to generation of a larger number of different antigens

Infarct size was assessed after 30 min of ischaemia followed by 24 h of reperfusion using Evans blue staining (1%) for delineation of the ischaemic area at risk (AAR) from the non-ischaemic zone (remote area) and 1% 2,3,5-triphenyl tetrazolium chloride (TTC) staining for demarcation of the viable and non-viable myocardium within the AAR, as described 19