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4.2 Iron overload and dysregulated metabolism Iron overload is a critical factor that drives ferroptosis and worsens ARDS pathology

Such an effect, however, was not caused by the oxidation of GSH to GSSG, as revealed by the HPLC pattern, indicating that GSH consumption was not due to the induction of oxidative stress

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aeruginosa obtained from patients suffering from chronic respiratory tract infections can induce ferroptosis and such cell death is closely related to the expression level and catalytic efficiency of pLoxA (Dar et al., 2018)