In early PD, surviving neurons can store some dopamine, buffering these fluctuations, but as the disease progresses and striatal storage capacity is lost, the short halflife leads to oscillating brain dopamine levels and the aforementioned wearingoff and motor fluctuations [96, 97, 98]

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4.5 Other renal disorders Dietary intake of the flavonoid quercetin has been proven effective in lowering blood pressure and restoring endothelial dysfunction in animal models of hypertension
Multigene families encode the major enzymes of antioxidant metabolism in Eucalyptus grandis L