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Furthermore, research has discovered that maternal factors during pregnancy, such as nutritional status, can impact PF formation and ovarian reserve in offspring [67]

Following transplantation, these cells must survive a hostile degenerative microenvironment characterized by nutrient deficiency, acidity, and inflammatory cytokines, which may induce cell death (e.g., pyroptosis) and further compromise their viability and function [36]

To determine which enzyme was responsible for the PQ cleavage pattern she observed, her team cultured bacterial colonies from saliva samples and tested their activity toward gluten-derived substrates, eventually identifying a subtilisin enzyme in Rothia mucilaginosa and Rothia aeria bacteria as the snipper (2,3)