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Second, a small number of observations restricts the number of regression parameters that could be reliably estimated due to the large loss of degrees of freedom

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people who thought e-cigarettes could help them wean off nicotine but who actually ended up consuming more of the chemical than ever before." Key to the light smoker successfully arresting their dependence is acceptance that they too are a real drug addict in every sense, that it's permanent, that in regard to chemical dependence that they are no different from the alcoholic or heroin addict