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Pathway analysis of siGSTO1 Bru-Seq data was also performed using IPA (Ingenuity Systems, Inc., Redwood City, CA) with genes showing fold change 2

PMID: 115 LiuZLiuBFengYZhaoLWangQHeHet al

Jama Intern Med

2) and (2) the seven reported suppressor mutations from the yeast model of disease can be all mapped onto the hydrophobic face of the regulatory domain that forms the BatemanBateman interface (Fig