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In low-resource nations, iron, folate, vitamin A, and iodine are in scant supply and their deficiency during pregnancy can contribute to multiple adverse outcomes in the mother and newborn

doi: 10.3389/fphar.2021.698905 291 WangS.ShengY.TuJ.ZhangL

Although cognitive outcomes (ADAS-Cog11 and DSST) did not achieve statistical significance within this brief treatment window, the imaging pharmacodynamics provided evidence of CNS penetration and on-target activity, representing an important translational milestone that now warrants longer treatment windows, biomarker-anchored endpoints, and more stringent gatekeeping against type I error

CD44 is of functional importance for colorectal cancer stem cells