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On the one hand, a large amount of pyruvate was catalyzed by L-lactate dehydrogenase to generate L-lactate and lactylated proteins in the cytoplasm

Esto permite modular el apetito antes de las comidas principales , lo que facilita la reduccin calrica sin caer en la ansiedad tpica de las dietas

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Exogenous ceramide induced senescent phenotype in young HDF at concentrations that mimics endogenous ceramide levels in senescent cells and recapitulated molecular changes of senescence, suggesting ceramides act as mediators of senescence (Venable et al., 1995)