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discovered that in mouse MCs, knocking down ROCK restored impaired fatty acid metabolism by modulating metabolic regulators like AMPK, PGC-1, and CPT-1 [78]

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It's a small, modified fragment of human growth hormone (HGH) engineered to keep the fat-burning signal while leaving out the effects on blood sugar and tissue growth that come with full growth hormone

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Despite these advances, translation into clinical practice remains limited due to challenges such as immunogenicity, systemic instability, manufacturing scalability, and regulatory complexity

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