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The 0.8kg average regain between plateau and week 48 compares favorably to the rapid rebound typically seen without medication support

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Circular dichroism spectroscopy, which we did to understand the secondary structure of our best candidate bovine IF, which indicated a predominantly helical secondary structure consistent with native folding, while computational docking predicted bovine and human IF to have optimal geometric complementarity and stabilising energies with B12, in agreement with our experimental binding data