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In intestinal homeostasis, BA-induced RORt+ Tregs exhibit potent anti-inflammatory functions, ameliorating colitis ( in vivo in adoptive transfer models ( Collectively, the gut microbiota generates a diverse BA repertoire that, through host receptors such as VDR, FXR, and TGR5 on Tregs, DCs, or tumor cells, profoundly regulates Treg differentiation, stability, and suppressive functions

The following skin parameters were recorded: hydration (corneometer), TEWL (tewameter), desquamation (standard D-Squame disc), wrinkles (trained dermatologist grading scale and PRIMOS 3D imaging system), and elasticity (ballistometer) at 4, 8, and 12 weeks

When specific organic acids are found accumulating, they often signal a metabolic insufficiency

He has about 150 PubMed publications, is author of the Moorfields Manual of Ophthalmology, and has an approximately 6M Euros research portfolio.