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Tau protein is essential for microtubule assembly and stability and is regulated by phosphorylation

Deletion of this loop was previously shown to hamper Rac1 binding 48

While these underlying diseases are clearly risk factors for severe COVID-19, the exact mechanisms responsible for the morbidity and mortality in the affected patients are unclear

A B cell receptor (BCR) can bind to an antigen and then signal for its presentation in the form of cleaved peptides to T cells through the major histocompatibility complex 2 (MHC II) on the cell surface