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The 40-item ALS Assessment Questionnaire (ALSAQ-40) has also been used frequently in trials, measuring five domains (eating and drinking, communication, activities of daily living/independence, physical mobility, and emotional reactions) with strong internal reliability, construct validity, and correlations with ALSFRS-R [60]

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Furthermore, N-Cadherin was found to associate with killer cell lectin-like receptor subfamily G member 1 (KLRG1), an NK surface receptor, thus driving NK exhaustion and immune evasion in tumors [149]

Topical GHK-Cu may help with skin texture and elasticity, but doesnt replace the volume that was lost