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Device considerations Premixed closed systems are recommended to avoid the following risks: inappropriate or incorrect dilution of liquid nicotine (the dilution process is not straightforward and relies on adequate product labelling) intentional or accidental ingestion or exposure through skin or eyes addition of potentially toxic or illegal substances, or contamination Therapeutic guidelines on nicotine toxicity state the potentially lethal oral exposure dose is 5 mg/kg

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Jay passed today at 12:00 EST," he also wrote via Facebook