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Previous studies have shown that melatonin decreased the formation of 8-hydroxy-2-deoxyguanosine, a DNA damage product resulting from free radicals, 60 to 70 times more efficiently than certain traditional antioxidants (Shirazi et al., 2012)

Any suspected side effects from these or any other medicines or research chemicals should be reported to the MHRA via the Yellow Card Scheme at yellowcard.mhra.gov.uk

This similarity suggests that the altered energy metabolism at baseline observed in ME/CFS may compromise the ability of these patients to respond to exercise in the same way as healthy individuals