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Such impairments closely parallel the mitochondrial respiratory deficits and elevated oxidative markers reported in cortical and limbic regions of depressed individuals, which would impair energy-dependent neuroplastic processes, intracellular signal transduction cascades, and activity-dependent protein synthesis required for synaptic maintenance, dendritic remodelling, and adaptive circuit function [138, 143]

The combination of cetuximab and -elemene not only promotes ferroptosis in CRC cells, but also promotes the expression of E-cadherin (epithelial marker) while reducing the expression of mesenchymal markers such as snail, vimentin, N-cadherin, slug, and MMP-9

These compounds are not intended for human consumption, medical use, or diagnostic purposes