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doi:10.1016/j.jogc.2022.04.004

Chemical Characteristics of Fluorine One of the hypotheses is that fluorine, with a dimensionless electronegativity value of 3.98 on the Pauling electronegativity scale, forms highly stable, polar covalent bonds due to its significant difference in electronegativity

To increase the entropy of water following exposure of HNE-bound hydrophobic regions of the proteins (14), other exposed hydrophobic regions of the same or different proteins will interact, i.e., this leads to protein aggregation of similar or different HNE-bound proteins (15)