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Material and methods : The study was a multicenter, pragmatic, stepped-wedge cluster-randomized trial

Caverzan A, Passaia G, Rosa SB, Ribeiro CW, Lazzarotto F, Margis-Pinheiro M (2012) Plant responses to stresses: role of ascorbate peroxidase in the antioxidant protection

Compound (NP7) is an anti-oxidant and could cross The BBB

Conclusion: This study combined network pharmacology and molecular docking to predict the underlying mechanism of Loganin against PMOP, validated by the in vivo mouse model showing that Loganin attenuated OVX-induced bone loss by inhibiting inflammation