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2 However, where these were placebo-controlled studies there was no statistically significant difference in the number of adverse events between the ashwagandha and placebo groups, 8,13,45,54,59 except for somnolence, which was noted to be more common in the ashwagandha group (21%) than in the placebo group (9%) in a trial in patients with schizophrenia

Longhitano L, Distefano A, Musso N et al (2024) (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease

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For instance, inhibitors of ferroptosis, such as Ferrostatin-1, can reduce inflammatory responses in keratinocytes, which may be related to the modulation of Th17 cell functions (152)