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It then travels to the thalamuss tertiary neurons, which in turn send pain signals to the frontal lobe, cingulate gyrus, and parietal lobe (Ho et al., 2010

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Immunol Lett 207:4655

Cadmium induces neuronal death in cortical neurons through a combination of apoptosis and necrosis, involving reactive oxygen species (ROS) generation and lipid peroxidation (155)