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Dong M, Lu L, Zhang L, Zhang Q, Ungvari GS, Ng CH, et al

These findings suggest that while FOXO4 is involved in the senescence pathway, it also plays a role in maintaining the viability of senescent Leydig cells by suppressing their apoptotic response, which could contribute to the accumulation of senescent cells [1]

Upon transportation into cells, cystine can be converted into cysteine by the action of reducing agents such as glutathione (GSH) or specific enzymes like thioredoxin