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The most effective concentration of HGF (10 ng/ml) was subsequently found to stimulate hippocampal neurons in organotypic hippocampal slice cultures which are more intact preparations similar to Dihexa (Figure 8A and B) further establishing a mechanistic link between Dihexa and HGF/c-Met

Its protective effects against neurodegenerative diseases are likely mediated through multiple mechanisms, highlighting its considerable promise for future PD therapy

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In advanced delivery systems using ionic liquid microemulsion (CaT-ME), GHK-Cu drives hair follicles into early growth stages within 6 days compared to 8 days for standard GHK-Cu and 9 days for minoxidil, representing approximately 3-fold improved local delivery