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Nerve Function Support: Vitamin B12 is critical for the functioning of your nervous system

CrossRef A Review of Research Trends in Traditional Korean Medicine for Nonalcoholic Fatty Liver Disease Na-yeon Kim, Mi-jung Yoon, Hong-sik Choi, Seung-mo Kim, Sang-chan Kim, Kyung-soon Kim The Journal of Internal Korean Medicine .2022

doi: 10.1016/j.sajb.2020.09.026 163 TijiSBenayadOBerrabahMEl MounsiIMimouniM

It was demonstrated that HG could cause the early activation of caspase-3/7 in SCs in vitro and in vivo , inducing caspase-dependent apoptosis in SCs ( in vivo study demonstrated that the apoptosis rate of RSC96 cells treated with HG for 48 h was increased by 9.72-fold, confirming that high glucose also elevated the mitochondrial pathway apoptosis-related Bax/Bcl-2 and cleaved caspase-9/caspase-9 ratios, and suggested that knockdown of histone deacetylase (HDAC1) could effectively inhibit HG-promoted mitochondrial apoptosis ( In addition to the above regulatory pathways, the role of HG on signaling pathways is critical in inducing apoptosis in SCs