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Brain hypoxia and ischemia after traumatic brain injury: is oxygen the right metabolic target

10.3389/frdem.2023.1222708 41 DashU

In a 2003 in vitro experiment by Khavinson and colleagues, addition of micromolar concentrations of the peptide to cultured human somatic fibroblasts produced a measurable increase in telomerase reverse transcriptase activity and a corresponding extension of telomere length across 1020 passages, with cell cultures continuing to divide beyond the Hayflick limit observed in untreated controls