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Science 365 , 14611466 (2019)

This is the core of how you calculate AHK-Cu dosage

Indeed, other studies have proposed such shuttle systems to supply demyelinated axons with lactate as an important energy sourcenamely, the astrocyte-axon lactate shuttle (Cambron et al., 2015) and the oligodendrocyte-axon lactate shuttle (Campbell et al., A common thread seen in these studies of neurodegenerative diseases is the perturbation of lactate

Furthermore, ZnT3 gene deletion inhibits the formation of EAE-associated aberrant synaptic zinc patches, MMP-9 activation, and disruption of the blood-brain barrier