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In mitosis, the kinetochore forms on the CCAN to connect the duplicated chromosomes to the microtubules protruding from the cell poles

5,384 Although vaccination attempts to eliminate tumor cells overexpressing mutant p53 began more than 20 years ago, currently, no vaccine has been approved for clinical use because various trials have shown no efficacy in patients

As Moura et al have verified, metabolically unhealthy obese individuals had lower mean peak systolic velocity (28.1 cm/s vs

The progressive accumulation of mtDNA mutations, along with increased reactive oxygen species (ROS) and disrupted mitochondrial dynamics, severely compromises mitochondrial membrane potential and exacerbates organelle dysfunction