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This binding activates MPST, which produces hydrogen sulfide (HS) and pyruvate, boosting mitochondrial respiration

The interaction of dsRNA with the helicase domain of Dcr-2 nevertheless has also revealed that the ends of the molecules with dsRNA structures play an important role in the activation of dicing as well as the innate immune response (section 7.2.1)

The role of mitochondrial transcription factor B2 (TFB2M), another regulator of mitochondrial gene expression, was observed in mouse TFB2M-KO -cells which had impaired mitophagy via defects in autophagosome-lysosome fusion, and this was associated with mitochondrial dysfunction, and deficient insulin release (Nicholas et al., 2017)