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Phospholipids typically consist of a hydrophilic headgroup, hydrophobic fatty acid chains, and a glycerol backbone (De Carvalho and Caramujo 2018)

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Proline-rich protein 11 silencing inhibits hepatocellular carcinoma growth and epithelial-mesenchymal transition through -catenin signaling

Our findings describe a role for mitochondrial plasticity as a mechanism for acute 5FU tolerance in CRC cells: mitochondrial changes acutely adopted by CRC cells in response to 5FU-based standard-of-care treatment result in increased mitochondrial biogenesis, which provides metabolic support for increased pyrimidine scavenging by UCK2 to resolve nucleotide stress