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Examples of these specific detoxification systems are the glyoxalase system, which removes the reactive aldehyde methylglyoxal, [4] and the various antioxidant systems that eliminate reactive oxygen species

For instance, mutation hotspots in the TP53 gene have been associated with tobacco smoke (e.g., codons 57, 158, 245, 248, 249, and 273) ( TP53 transversions are well characterized for tobacco exposure, potential biomarkers for radon remain largely hypothetical and require further investigation

They are available in a variety of formulations: both over-the-counter (OTC) and prescription