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Criteria for diagnosis of POEMS syndrome requires both major mandatory criteria, one of three other major criteria, and one of six minor criteria

These disparate results might be explained by variables including age, sex, and antibiotic treatment schedules, all of which change the GM and hence affect immune function

These products have not received the safety and quality review of the FDA, and have not adequately been tested on humans like other more rigorously tested products like GLP-1 drugs

References: Adrian S, Scherzinger A, Sanyal A, Lake JE, Falutz J, Dub MP, Stanley T, Grinspoon S, Mamputu JC, Marsolais C, Brown TT, Erlandson KM