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10 Consequently, many clinicians have avoided the direct use of GSH supplements and instead focused on GSH precursors, such as N-acetylcysteine, to boost endogenous production.* 11 However, in 2015, a clinical study of pure powdered glutathione increased erythrocyte, plasma, and lymphocyte glutathione levels after six months of use in humans, suggesting that some is absorbed after all.* 12 Finally, an oral glutathione that increases blood levels 2.5 times more than other forms

Low magnesium levels are associated with depressive symptoms As of 2018, it was estimated that about 48% of the US population consumes less than the recommended amount of magnesium (DiNicolantonio et al., 2018)

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The result is shown in Extended Data Fig