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Additionally, mitochondrial function was improved post- HSYCR treatment, indicated by increased mitochondrial membrane potential and decreased Ca2 + levels

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PGE2 Inhibition NSAIDs are used for pain and fever reduction, primarily through COX-2 inhibition PGE2

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The high risk of metastasis in these patients may be associated with epithelial-mesenchymal transition (EMT), which is induced by several transcriptional factors such as Snail1, Smad2, and Twist1/2

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Mangiferin treatment ameliorates fatty liver in fructose-fed spontaneously hypertensive rats (SHR) by inhibiting hepatic DGAT2, which catalyzes the final step of triglyceride biosynthesis (103)

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