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Vaysse PJ, Gardner EL, Zukin RS

The theory of metal-induced aggregation is supported by numerous studies tying metal concentrations in the brain with AD, PD, and amyotrophic lateral sclerosis (ALS) in in vivo and in vitro studies employing recombinant proteins ( In this review, we will focus on -synuclein, one of the major proteins implicated in PD, and its interactions with metals, specifically, its interaction with Mn in oxidative stress, protein aggregation and neurodegeneration

Yes, the dose and how often B12 shots are given can change

NAD+ IV therapy bypasses all of that the NAD+ enters the bloodstream directly and is immediately available to cells