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Saline is fine for many single-peptide reconstitutions but it is the wrong solvent for any vial containing a copper peptide

Sterile water has no preservative, so once the vial is punctured, bacteria can grow

These results position cagrilintide monotherapy as less effective than semaglutide for raw weight loss but still clinically significant and far superior to placebo

Whether CagriSema ultimately occupies a meaningful commercial position in the obesity market will depend substantially on how the FDA evaluates the REDEFINE evidence package and how payers and prescribers weigh a well-evidenced but second-ranked option against the existing approved standard.